I’ve only had 4-inch versions of the 25s, a couple of 25-5s and a 25-9. They all shot high with my handloads using a 260 gr Keith bullet and Unique or 800X. With that in mind, I’d think using a lighter weight bullet, as D Walt suggests, would be a good idea. His Bullseye load sounds like an ideal starting place, but I haven’t tried it. I just might!