I was loading 45s with the 1050. Got low on powder so opened new can(231) and dumped it in. I usually check powder charges every 200 or so...about 15 minutes. Well I skipped that step for a 1/2 hour or so and when I did check. the charge was a grain heavy at 6.4 gr. That was a holy cow moment. I dumped the powder and got another can with the same lot number as the previous powder and it was right back at 5.4 gr, I hadn't dumped all the rounds out of the catch bin so I have about 500 suspect rounds I have kept separate. My question to y'all here is this... I happen to have a Ruger Blackhawk Convertible with the 45 ACP cylinder. Rather than tear all them down. Do you think they would be safe to shoot in that BHawk?? Yeah...I know. Grasping at straw. I still don't know why that powder threw such different charges. New can...just different lot number.