In factory form, yes, and much more popular.

I think Sasha Siemel's Smith & Wesson .44 was perhaps a .44-40, as he also had a Winchester-92 and the ammo was far more plentiful in Brazil than was .44 Special.

He used these and other guns, inc. a Registered .357, to kill big jaguars,as well as his famous spears.

I chose .44 Spcl. in the survey, as the cylinder walls would be thicker and I could handload warmer ammo, although I'd stick to probably a 250 grain bullet at some 900 FPS.

The .44-40 was that hot, but the short 200 grain bullet had less sectional density and wouldn't penetrate as well on really large animals. The Winchester ctg. is also harder to handload and wears out brass sooner.