This is the place where I disagree with the internet gurus and so-called experts.

Once the rounds start flying and the target gets their adrenaline dump, they'll be moving very quickly and erratically; the first shot has the best chance of landing and thus should be the one you're counting on to do the job. Anything after that is jelly.

Might not be the prevailing expert opinion... it's just mine.

EDIT to add: The rest of the post is very true. Far too many variables.