You know, "best" is very subjective - "Best for what?"
For just a fun gun, lightweight, accurate, and reliable, I like this Ruger MkII (the best of the Mk series, in my opinion) modified with a Tactical Solutions lightweight compensated upper. Easy to pack in the field, too.
If you are talking target shooting, none is better than this High Standard "space gun" made in the heyday of quality and accuracy. This eats anything and puts it where you want it every time, and without fail. More bells and whistles than a freight train, all designed to make it the best. These guns ruled the bullseye circuit for years and years. I was so envious of those that had them when I did competition shooting years ago.
As for revolvers, I would never part with this S&W Model 18-4 for any reason. Greatest training revolver ever made.
John