Shoot them with no worries. I've never had any shot shells with plastic capsules "gum up" anything. I've also shot crimped brass shot loads.
It's not like you are going to be shooting hundreds of them at a time anyway, I shoot maybe 10 a year at rattlers.
I use them in .22 LR, .22 Magnum, .45 ACP and .45 Colt.
Even the .22 LR ones will mess up a snakes head at 4 feet.
