The OP poses a good scenario.
I stopped being out and about after sunset (about 5 years ago) unless it is an ABSOLUTE necessity. Living on the outskirts of a city where there is a shooting almost every day within a 2-8 mile radius of me,it seems like a good idea.

I would think that the reaction time between realizing you are about to be/or are shot by whatever weapon would negate any meaningful response by you. In a drive by shooting, the car is moving and after the shooter fires,the car speeds away leaving you with no time for any action even if your able. JMO
I believe that my response would be get to the ground as fast as possible (intentional or not). This would provide a smaller target if the shooter continues to shoot.

Be SAFE out there, it's a crazy time we live in!