30-06 has a wide range of applications, along with a a huge spread of bullet weights and appropriate powders. So the first thing to think of is "What do I want my 06 to do?"

For hunting, choose the bullet weight you've used before. For target with a shorter barrel, a light, flat base bullet might work best. For target out to ~800yds 165-175 is often a sweet spot. If you're going to stretch the 06 further out, even heavier bullets will provide the BC to stay supersonic to that range - if your barrel is long enough.

Cartridge-Base-to-(bullet)Ogive measurement (CBTO) may become more important to accuracy than COL. If you're willing/able to single load, a longer cartridge than will fit in your magazine can give a bullet a "jump" that it prefers but will not fit in your mag.

These, and much more are new considerations. So yes, there are significant differences from pistol.