My home stuff usually is just whatever I was carrying that day. The last few days it has been my Beretta 96G Brigadier Elite II. Prior to that it was my 92FS Centurion. Before that, my HK USP Compact and before that it was my S&W WVSP contact 4566TSW. Tomorrow it'll probably be my GLOCK 17 Gen 4. I wear guns like my wife wears purses.
Even the long guns rotate. Right now the FN SLP is doing home duty. Previously it was a MSAR E4 AUG. Maybe for Turkey Day I'll mix it up and use my .50.Cal Hawken BP rifle and .44 Cal Colt 1851.