I would have to put in a vote for a Thompson Center / Contender . Yes it is a handgun ... better described as a Hand Cannon.
My calibers.
.35 REM.
.375 JDJ.
.41 mag . 10 in Bbl.
.45-70 Govt.
I had a 44 mag . Sold it as my .41 mag. Shot better.
The hottest .41 load I put together and through the Contender was a 300 gr. Bullet for a .405 lever gun ( .412 dia. Softpoint) 17 gr. of H110 .
Actually handled it like a dream. No problemo.

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Dino in Pittsburgh's Rat Pack