Tim357 , give it a try . I some time back read about a guy that was wanting to shoot 148 gr wadcutters . He either only had 4227 or someone gave him a bottle . Anyway he used , if I remember correctly 8.0 grs . It shot dirty , but he was very impressed with the accuracy . I am sure that what you read from Mike Ventorino is a safe load to use . It will probably shoot somewhat dirty but the accuracy should be great . Like Mike said , use a magnum primer to get more consistent ignition and more complete ignition . Shooting out of a longer barrel will help also . Lets us know how it works for you . Regards Paul