The standard for full power loads with a 240 jacketed bullet is 24-25 grs of 296/H110 for close to 1400 FPS out of a 7.5“ Ruger and about 1750 FPS out of the 18.5” Ruger 44 auto and about 1800 FPS out of a 20” Marlin. It seems that so many handloaders use these loads with complete sastifaction and safety why use anything else? Top charges vary with different manuals with Hornady going to 25 grs with their pre XTP HP but it doesn’t really matter. 24 grs with the Hornady bullet chronos about 1815 FPS out of my 22” Ruger and 25grs only runs a few fps faster. When you get to the point of compressed loads of 296 it stops responding to increases.