You can get by nicely with two powders :

1.) A Fast powder like Bullseye for light and target loads ... this includes, 700X , Red Dot , 231 , HP-38 , Titegroup and Accurate #2

2.) A slower powder for heavier +P and low-mid level magnum loads...
like Unique ... this would include : Accurate #5 , Universal , SR7625 , Power Pistol and HS-6

For heavy Magnum loads you may wish to add a third, slower , powder like 2400 or Enforcer , Lil Gun , 296 , Accurate #7 , Accurate #9 and H110 .
I tried for years to get Unique to "do it all " and although versatile it needs help at the light end and heavy end ... Bullseye powder was my first clue that Unique just wasn't suited for target / light loads and I wasn't going to find one power to do everything .
Load Safe,
Gary

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