I can tell you , from personal experience that with a 210-220 gr cast bullet that 7.0 grs of HP-38 , Ramshot Zip , Accurate #2 and IMR 7625 (now discontinued ) makes exceptionally accurate loads . I felt Accurate #2 was the most impressive . One thing that I really like about Accurate #2 is that it's " not position sensitive " according to Accurate Powder Co , yet it does not burn hot , like Titegroup powder .
Last time to the range I tried 2 of Elmer Keith's load for the 41 magnum , 4.5 grs of Bullseye powder and 7.5 grs of Unique . The Bullseye load is an ideal target load . The Unique load made a real nice " shoot all day " mid range load with POA = POI for both . Of course both loads used his design 220 gr cast bullet , H&G 258 . Any cast bullet 210-220 gr will work just fine as well . Regards Paul