To get a .22 upper for a 39/52 frame would take some serious money. While some of the owners of these pistols may opt for a conversion unit, I do not think there would be enough interest in it to may it cost effective. If you want the one frame, several uppers concept look to the Eaa Witness pistols. A friend has several uppers that will fit on one frame.

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USMC 69-93 Combat Pistol Inst.