I currently use it in .41, .44, and 45 Colt loads with cast bullets. 7.0 grains works in all of them. However, next time I load .45 Colt loads I will up the charge due to the case size.

I have a 4 pound jug of it and if need be, I can use it in the other pistol rounds I load for. I have used it for 50 years, so why change?