Yeah, there are much better powders than 4227 for the 180-gr .357s. Lil' Gun and - believe it or not - Blue Dot (use Alliant's currently published max data for a great load, the one that I carry in my 3" gun).
I find the 180-grainers stout out of a K-frame, but completely controllable. We're not talking .500 Linebaugh here by any means.