The conventional wisdom of the day indicates 1600 fps is where the micro groove will shoot cast bullets well. NEF/H&R have used micro grooved barrels for several years and I seem to have several of them.
My 22" barrel also has a factory recoil pad on the other end, which helps a lot! Since I don't live in bear country, I try to send a 405 gr cast bullet downrange as accurately as possible. This 100 yard target was shot with a Rem 400 gr JSP, but cast will do just as well.
One advantage to using this load is the tremendous reduction in recoil!
Moving a little faster, around 1475 fps, this 300 gr Rem JHP uses 20.0 gr of Blue Dot .
I've shot as much as 25.0 gr of Blue Dot with that 300 gr bullet, but 20.0 gr was much more accurate and recoiled less.