I am BRAND new to this. I have found data for imr4227 in a 350 grain bullet but not the 300. Is there another powder I can reference it too, or should I use another powder?
Thanks

300 Grain LSWC + G.C.
H4227 41.8 gr. 1,615
Lil'Gun 40.0 gr. 1,775
2400 29.0 gr. 1,250 (mild & PLAIN base bullet)
2400 31.0 gr. 1,330 (mild & plain base bullet)

300gr LSWC 42.0 gr H4227 2,219 fps 2.190" CCI LPM guest
This is one of my commercial .500 bullets fired from a 15" OTT Encore barrel with integral break.

Plenty more data out there just Google 500 S&W Reloading.

But off the top of my head I'd think that the Speer #14 would likely have some data. I'll find it and post back.

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Thanks
I really do appreciate it. It looked like I could use the H110 for reference, but wanted to make sure.

ummm ... dont do that.
H110 is NOT IMR4227
these things aren't linear in their behavior. Each powder has a unique performance curve.

if we were talking about Win 296 and H110, that would be a different matter because they are the same powder, rebranded.
This is a fairly rare exception and unless you have solid confirmation of two powders being alike, treat each as its own religion.

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it just needs more voltage