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Barnes XPB 200 gr #30554
H110 will provide best results for your listed powders
Most accurate powder I have found for this bullet is #9, velocity will be just under what H110 produces by about 40fps in 7.5" gun but suspect won't be that out of 3.5"

Barnes XPB 275 gr #30548
H110 for powders you list
Lil gun produces highest velocity, but for accuracy I prefer Enforcer or #9. With this bullet I don't see big accuracy spread for any of the suitable powders for 460 cartridge.

Cleanest burning powder for either will be N110.

H110 work well across the board with any type bullet or weight and almost always will produce highest velocity.

For bullets 300 grains and heavier 4227 is a great choice- my go to currently for 300 XTP MAG

4198 works well with very heavy lead bullets 395 grains to 740 grain but most of these bullets can only be used in the BFR with its 3 " cylinder and its faster twist rate.

Suitable common powders (US) for 460 are A9, 2400, Enforcer, N110, H110, Lil Gun, 4227.

Powder which are suitable under certain conditions would add 1680, Tin Star, Trail Boss, 5744

Powder I have not personally tested which may work are 4100, 300-MP

Hope this is helpful
Be safe
Ruggy

At 200 yards BC is off little concern- bullet weight makes much bigger difference.

In the field my current preference is 7.5" barrel gun -open sights or dot and 10.5" scoped 2.5x8. depending on what and where I may carry both.

That said I have taken game with every barrel length made except the 14" comped version, and that only because I rarely hunt from a blind were I find them practical.

My bullet preference for hunting is 260 grain CPS by Northfork Technologies. Off coarse there are other good choices depending on what you are chasing, nothing wrong with the Barnes you are going to load- I have them on Bison, Bear and Hogs to good effect.

I have used plenty of Barnes in the field and they worked well for us.

When run dogs on hogs I use and ES model with 250 Barnes XPB on top of 100% case fill of Trail Boss- easy on the dogs and everyones ears and no flash - even this reduced load produces complete pass through on 200 pounders.

be safe
Ruggy

Load them in your 460 cases if you want good results.

You can load them with 45C data if you seat them to same OAL used in 45C, they will be completely hide in the case. The object here is to get rid of the 1/2" of free bore you have when shooting 45C

be safe
Ruggy

Just looking at those grips on 460 hurts my hand lol