From the link:
"These loads are safe in all large frame Ruger revolvers, TC Contender, and Colt Anaconda. These loads are safe in all modern Model 1892 leverguns as well as all Winchester & Marlin 1894’s. These Heavy .45 Colt +P loads are NOT intended for the New Model Vaquero (small frame). DO NOT USE IN ANY OTHER FIREARM."
Ruger makes a nice DA .45 Colt. Good luck in your decision.