see the following
460 S&W: Velocity / Barrel Length
Obviously the velocity of any given bullet can be several hundred fps different out of the same gun dependent on the loading.
Any barrel length 460 S&W with the correct bullet will be no issue with/on Grizzly.
I personally carry/use a different bullet for hunting than self protection from big bear.
Note, I have personally been successful with 460 on grizzly.
be safe and good luck
Ruggy