S & W's Personal Defense (PD), Military & Police (MP) and Night Guard (NG) are all closely related.
I think overall, the Night Guard (NG) series offers the best value, especially for concealed carry. Next is the Military & Police (MP) line, although I only like the 340CT and PC-325 Thunder Ranch.
I find the NG series more "pointable" due to the higher profile XS/C&S XD sights. Finish is more durable than M&P's.
The 325 Thunder Ranch is a real deal. It's a $2000+ revolver if you had to start with a base revolver and have it customized.
Forum member ENH has some nice customized revolvers in these series. He has photos posted in several threads.