Radworm:
The Big Dot front sight is a few thousandths taller than the stock sight, but it's not mattered on my M&P40C. I suppose a Kydex holster with a "channel" for the front sight might give you problems, but leather or nylon shouldn't matter at all. (I use leather, but have a Kydex holster - from an M&P40FS - that doesn't seem to care.)
Still trying to get my hands on a Shield, but I don't see any real difference likely.
(Hint: Buy the Kydex from somebody who'll let you return it
....)
Regards,