I have the 22s version of this pistol, and the difference is that it's all steel/stainless steel, no aluminum alloy in the gun.
I've recently used up all of my Federal 550 round bulk packs accumulated from the very early 1990s. I remember that seldom, if ever, having a defective rimfire primer charge in any of those older Federal rounds.
With the newer Federal 550 bulk packs, I'm experiencing frequent fail to fire rounds, though most will fire if rotated to allow another strike on the primer rim.
I also had some early 90s bricks of Rem Thunderbolts, and WW wildcats, and occasionally, one of those wouldn't fire either, however, rotating those cartridges in the chamber seemed to remedy the problem as well.
A few years ago, Remington target (blue) ammo that I had just bought at Walmart, ftf about 30% of the time.
In all fairness, Remington picked up (via UPS), the defective rounds and boxes, and they did confirm the rim/primer charges defective, plus, they paid me for the 2 boxes of ammunition. Good outfit they are!
Switching to Federal Gold Medalist target 22 lr ammo, (circa 2002), that pricey stuff was absolutely reliable, as was
any CCI rimfire ammunition that I've recently used. Even their promotional Blazer fodder fires every time. Perhaps it's just the luck of the draw.
FWIW: My S&W model 41 duplicates the ftf syndrome with all the above described defective rounds, so for sure it's not an issue with My S&W 22s pistol.
IMO, production quotas seemingly have reduced the quality of much of the current 22LR ammunition offerings.
Just My observations, and .02.