Does anyone have a good suggestion on a quality after market grip for a 5906 that is the same profile as the stock grips or close to? My Wife also shoots this and her hand fits the stock grips. Any help would be appreciated.

Hogue makes some and they are really nice looking and are sold on Amazon

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The Lord cometh and right soon

But the Hogue's (rubber or wood) are much thicker than stock.

Uncle Mikes, Pachmayr and others used to make replacement grips but they have all stopped. Sometimes however these grips pop up new and/or used on places like eBay and GunBroker. Make sure you search for multiple terms like 5906, 5900, 59XX, etc.

I have read lots of complaints that the Hogue rubber grips are much thicker than the factory delrins. Although very pricey, I have a set of Crimson Trace Lasergrips on my 5906, and they are very close to the factory thickness. For affordability I would just get factory delrins, as mlk18 stated use lots of search terms in eBay & GunBroker--you can also add the S&W 4000 series to your search:4006, 4046, etc.

Thanks for the help