As a matter of interest, I checked Powder Valley to compare powder prices between Titegroup and Trailboss in the .44 Special:

Using the five pound price of Trailboss - $16.60 per lb
Using eight lb price of Titegroup - $12.62 per lb
No hazmat or shipping figured.

Using Hodgdon's own data to get a factory equivalent fps with a 240 gr lead bullet (roughly 750 fps) :

Trailboss - 5.2 grs.
Titegroup - 4.0 grs

Cost per 100 powder charges:
Trailboss - $1.23 per hundred
Titegroup - $. 72 per hundred

Whether the extra cost is worth it depends on the reloader. You will NOT double charge with Trailboss, while that COULD happen with Titegroup. If a newbie starts loading with a progressive press it might be worthwhile for him to do so with the first five pound can. It just might be cheap insurance.

FWIW
Dale53