OK - update on my K22 with the misaligned barrel. Took it to my 'smith who confirmed that it was canted to starboard.

He tightened the barrel into the frame to bring her to 12 o'clock, and align the ribs on barrel and frame. Hard to beleive they let this out of the plant in 1952, but as far as I can tell, no one had ever tampered with it.

Tried her in the backyard a bit ago and sure enough, groups came pretty much to center. Tried a few different types of ammo. It does NOT like some 30-yr. old Federal promo ammo that has just a bit of corrosion on the bullet. Recent WW Super-X does well, 1' at ~20 yds. What was really surprising was what it did with with some CCI .22 LONGS I had on hand. Just under 1" at ~20 yds.! Mind you, I said LONGS, (not Long Rifles), a semi-obsolete .22 round that has very questionable usefulness.
Will try some other stuff later on.

Thanks to all for their input on this..............