It's hard to go wrong with a 240gr SJSP's. They deliver a big punch with good expansion. I would shy away from Remington, the lead seems harder than other brands.

I just switched to Hornady's Leverevolution 225gr rounds but haven't taken anything with them yet. Long range accuracy is superb from my 7 1/2" Ruger Super Blackhawk, and from what I've seen with the FTX bullet in other calibers they should be devastating.

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Fast is fine;accurate is final