158gr soft point won't expand on people, at all, and will whistle through and still be very dangerous for quite a distance.

I'd use it for practice, hunting things that need extra penetration (hogs as an example), or as a SHTF stash, but not for self defense.

K frames will wear out much more quickly with the full house 125gr loads, but I saw hundereds of 125gr Remington .357mag rounds fired through model 66s back in the day and very few had any issues.