I'm wondering if you read the Chuck Hawks article you referenced.
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The potential problem is the 10mm Auto cartridge itself. Powerful for a true auto pistol cartridge, it is not particularly impressive when compared to the popular magnum revolver cartridges.
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Hornady offers a 10mm factory load using their 200 grain jacketed hollow point XTP bullet (MV 1050 fps, ME 490 ft. lbs.). Hornady recommends this bullet for "medium game," which would presumably include wolf, cougar, jaguar and black bear but not grizzly, brown and polar bear.
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Bullet selection for any of these should tend toward the heavy bullets for the caliber, to maximize sectional density and thus penetration. Jacketed Soft Point (JSP) or hard cast bullets are the usual choice. Federal, for example, advertises their CastCore (hard cast lead) bullets as, "excellent for back-country self-protection."
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Note the key word--penetration.