I use the 240 XTP over 23 grains of win 296 and CCI or WLP primers. I do not use the magnum primers and have never had one fail to fire even under very cold conditions. Accuracy is excellent out of my 9 1/2" Super Redhawk. It handles big Missouri whitetails with no problems and they make very large holes causing massive internal damage. I have also taken whitetail with the 180 grain XTPs also with excellent results.