I shot a .460 ONCE. Way too much handgun for me and I can shoot a buttload of .41 magnums. The 500 actaully felt better but still too much for me in a handgun.
If I need that much power I'll use my Marlin Guide gun in 45/70, or keep packing and shooting my .41 mags with the appropriate load for the task at hand.
Looks like a death ray revolver with that brake to me and I would not want to be on the wrong end of it