Unique is not perfect, but it will do more than any other one powder in handguns. It won't give quite as high velocities as magnum powders, or be as economical as some of the fast ones. You can load almost every handgun caliber with it from .32 s&w to .45 colt, and load the magnums to within 200fps of max. Universal seems to be an acceptable substitute that meters better, but seems to have more of a tendency to have pressure spikes.

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dd884
JMHO-YMMV