I have the 45 midsize
I've put about 200 rounds through it at the range. The accuracy is phenomenal. My experience ,thus far, has been completely positive. 2 inch "3 shot" groups at 15 yards, which for me is excellent.
The 45 mid, and 45c have the same 4" barrel so it pretty much depends on which grip you prefer. I don't like grip extensions on magazines, and i like a full grip, so for me the midsize model was the one to go with. hope that helps.