This isn't based on my own experience, but since buying this gun I've wondered about the range and lethality of the .22. A lot of people, at first thought, see it as a weak round. But I think it is a rather versatile and potentially lethal round.

Maybe this is old news to you guys, but I read this posting by a guy who shot a 22 at a frozen turkey wrapped in three layers of street cloths at a range of 250 and I think also 300 yards. All rounds that hit, penetrated through everything.

Here is the link: Lethality of the 22LR- Results! - Sniper's Hide Forums

There is also these two videos of a guy shooting rock hard avocados at a range of 225 yards:
Pt 1: http://www.youtube.com/watch?v=CElxKOv8iPc
Pt 2: http://www.youtube.com/watch?v=43ZeycTo7iI