Hired Gun,
I am of talking about two different cylinders (as is always the case with all combo guns) but the same hammer strike. I believe you when you say some folks try to use LRs in a mag cylinder, but that is not the issue here.

The question is whether 22 mag ammo has better primer distribution than 22 LR ammo. You are correct that FTF often is caused by weak springs, excessive end shake, and similar problems that gunsmiths would know about. That's why I chose the smithing section to ask this question. However, there can be no question that some lots of LR ammo, especially some (not all) bulk packs, are notorious for significant FTF; CCI is not one of those, nor is 22 mag ammo.

Thus the question: does 22 mag ammo have more reliable primer distribution than 22 LR ammo?