There are ".41 Special" conversions around that have been converted from L frames and from Ruger GP 100's. They are 6 shot. I guess a Python could be converted also. The "Special" is, of course, a lower pressure round, generally limited to about 1000 fps. The L frame sized gun does not have a large enough cylinder to handle full power .41 mags when opened up to that diameter. In the 60's some Pythons were converted to .41 mag. They are probably dangerous to shoot with full power loads. You see them pop up on GB every now and then, always claimed to be a "factory" conversion, but it didn't happen.