I'll have to admit I'm a Glock-Lover and the .40 S&W Round.
Glock 22 & 23 with belt holsters.
Glock 27 (Baby Glock with 10-round mag) with the Desantis Pocket Holster.
......
But I keep going back to the Hammerless J-Frame with the Densantis Nemisis pocket holster. Something about that long deliberate trigger pull just really makes sense in a SD pocket gun.
I almost always wear Kahki pants with loose front pockets, and the J-Frame fits real well. I have a pair with pockets that are smaller, with the gun they are too tight, so I don't wear them when carrying. I always wear a belt.
And yes, I have to move my pocketknife and Streamlight Stylus Pro (2AAA) flashlight to the other front pocket.
J-FRAMES RULE !