The G-22 didn't serve your needs and you are transistioning from a revolver. The 3rd gen S&W are great, strong but are heavy...however they are quite useable. Some aftermarket grips/sleves are avalible to give more positive grip. I like the S&W10xx series 3rd gen because of the ballistic potential of the 10mm cartridge. The 10mm with 0.400" bullets, runs from 40S&W ballistics and up into the near 41 magnum potential. The ammo selection commercially can pose some avalibility limitations, but I handload to avoid those issues.

If you prefer something lighter you may want to consider the M&P line which has interchangeable grip panels to better fit you grip feel.

I do shoot a Glock 29 10mm also which has provided exceptional service digesting even the full potential loadings of 10mm.