I think this is a big case of just how much you stalk your target when hunting. The .45 ACP was never intended for hunting. But I know guys that have used Beretta 92's in 9mm for hunting. And they got in darn close to do it and claimed it was one heck of a rush. I can only assume bow hunters do and feel the same way. SWC ammo for .45's is typically loaded as target paper punching ammo and loaded soft enough to cycle reliably but get you back on target fast. If you wanted to hunt I would try and find a good 185 or 200 grain SWC and load it out to the max stats allowed in a 1911 and see if you can shoot them accurate enough at fifty yards MAX. Add to this I would drop in at least a fresh spring if not a heavy one. You might even add one of the nylon buffer bits. I just don't see this as a good idea unless you are going all Predator style on them and slapping them in the face first before you shoot them. I'm not the avid hunter but I know at least a little bit about 1911's.