I have a 25-2 with .456” throats, a 625-8JM and 625PC with .452” throats. The 25-2 originally had chamber alignment problems. I had to grind the cylinder locking bolt a little and fit a thicker hand to correct the problem. I also had to recut the forcing cone. Now the bullets hit in the middle of the forcing cone and it no longer spits and shoots very well. I suspect that the typical loads I shoot, a 200 Hornady FMJ-CT with mild loads of 231, shoots well because it is a jacketed bullet and the base doesn’t get burned by blow-by in the large throats, and the large pistol primer in the dinky .45 ACP case pounds the bullet through the oversize throat into the barrel before the power can develop enough pressure to blow by. That is just a guess. The 25-2 and 625s all shoot very well.

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Tom