If by "moderate amount" the above commentators actually mean shoot all you want because +P is loaded well below maximum allowable pressure and poses absolutely no risk of damage or wear then they are correct.
It is a myth that +P is in any way a "hot load." It is, actually, very mild running some 3,000 PSI below max pressure. I think a couple thousand rounds of +P will break in a Model 36 nicely.
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