I have at various times in the past carried a few different small 22 LR
handguns for defense, a 2" S&W 317, an old Beretta 948 and an old
LLama 1911 lookalike. But then I did a bunch of penetration tests in
pine, cedar and wet newsprint with the 22 LR, 25, 32 and 380 acp. I
don't believe anyone should deliberately choose the 22 for a carry
weapon unless nothing else is available.