I often carry my 6" 10-5 in a Bianchi IWB K-frame clip holster. With heavy jeans or tac pants like Blackhawk it's no problem. I carry almost exclusively IWB.

I have also carried a 6" full lug Ruger GP100 that I set up for CC with a spurless DAO hammer and XS Big Dot sights. I'm also 6"4" and built like a bean pole so I have more leg to hide a longer revolver.