So I guess I can sum this up with, numbers dont matter unless they do
Seriously, low numbers are always good in older guns. Single and double digits are collectible on their own. Sometimes triple digits are expensive too.
Know numbers, 666, 911, and similar also have a following and can add value.
The rest of the numbers would have a connection to a buyer or seller at a personal level, your birthday etc. Dont really have any cash value, just bragging rights.
So after all that I should have bought the Python with a mid to low three digit serial number last week for $2500 in great shape.
The gun I was interested in (and started the thread about) a M41 with a 4 digit sn is still over priced...
The hunt goes on