When I started reloading in 75 I settled on Bullseye,Unique and 2400 for my three " go to" powders.....over the years I have loaded and shot about everything that has been on the market.....but I still load my 4" bl 41's,44's & 45 LC's with Unique.....used to buy it by the keg and have shot thousands of cast bullets downrange with it.....use an old Lyman measure to meter it. I can load heavy in the shorter barrels and not have a huge muzzle flash.