It depends what holster I am using. Right now, in the N82 pro, safety is off. You have to twist to release in this holster, and I don't want the added step of having to disengage the safety (although I always practice my draw with a sweep of the safety, just to be in the habit....it's actually a quite natural motion while bringing up to sights).

In a Remora or Pistol Wear, safety is always on. I didn't think I would like having the safety on the Shield and would leave it in the "off" position, but find myself using it more often than not.

Tracy