Stay within the 700 to 1600 fps range and you will be fine . These bullets do not have a gas check, and are rated as 10 on hardness, so might lead if loaded over 1600 fps. Softer bullets are better in revolvers where they have to slug up to fill a cylinder throat. I have had some bullets that leaded because they were too hard to accomplish this. Some believe that the harder the better, but that ain't necessarily so when it comes to revolver's.
gary