I would think so. About anything under 650 ft/sec should be fine. My normal load is 3.0 of Unique with 145 grain 0.361" cast bullets. My first load was 3.5 grains of Unique and 125 grain .358 cast bullets, and it worked well also. But I ran out of those bullets several years ago. Just be sure you don't double-charge your cases.
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